The backbone structure of this family of proteins has been determined however the function remains unknown. The protein has an alpha and beta structure with a ferredoxin-like fold [[cite:PUB00040528]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00040528":{"PMID":16927360,"ISBN":null,"volume":"65","issue":"2","year":2006,"title":"Structure determination of a new protein from backbone-centered NMR data and NMR-assisted structure prediction.","URL":null,"raw_pages":"480-9","medline_journal":"Proteins","ISO_journal":"Proteins","authors":["Mayer KL","Qu Y","Bansal S","LeBlond PD","Jenney FE Jr","Brereton PS","Adams MW","Xu Y","Prestegard JH."],"DOI_URL":"http://dx.doi.org/10.1002/prot.21119"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":33,"pathways":0,"proteins":33,"proteomes":33,"sets":0,"structural_models":{"alphafold":32},"structures":1,"taxa":55},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":5},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}