{"metadata":{"accession":"PF11303","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR021454","hierarchy":null,"name":{"name":"Protein of unknown function (DUF3105)","short":"DUF3105"},"description":[{"text":"<p>Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":28,"interactions":0,"matches":4029,"pathways":0,"proteins":4026,"proteomes":3090,"sets":0,"structural_models":{"alphafold":2461},"structures":0,"taxa":5244},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":86,"alignment:full":2092},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}