{"metadata":{"accession":"PF11127","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR021309","hierarchy":null,"name":{"name":"Inner membrane protein YgaP-like, transmembrane domain","short":"YgaP-like_TM"},"description":[{"text":"<p>This domain is found in proteins from bacteria and archaea, including Inner membrane protein YgaP from Escherichia coli, a membrane protein with a rhodanese domain (Pfam: PF00581) that may have sulfurtransferase activity. YgaP adopts a dimeric assembly. This entry represents the transmembrane domain. It consist of two slightly tilted alpha-helices [[cite:PUB00100968]]. Structure prediction suggests that this region may homodimerise to form a 4 helical bundle.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00100968":{"PMID":24958726,"ISBN":null,"volume":"289","issue":"34","year":2014,"title":"Solution NMR structure and functional analysis of the integral membrane protein YgaP from Escherichia coli.","URL":null,"raw_pages":"23482-503","medline_journal":"J Biol Chem","ISO_journal":"J Biol Chem","authors":["Eichmann C","Tzitzilonis C","Bordignon E","Maslennikov I","Choe S","Riek R."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":25,"interactions":0,"matches":11132,"pathways":0,"proteins":11110,"proteomes":7897,"sets":0,"structural_models":{"alphafold":7483},"structures":1,"taxa":11931},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":69,"alignment:full":5957},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}