{"metadata":{"accession":"PF11102","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR021308","hierarchy":null,"name":{"name":"Group 4 capsule polysaccharide lipoprotein gfcB, YjbF","short":"YjbF"},"description":[{"text":"<p>This family includes lipoprotein GfcB (YmcC), involved in group 4 capsule polysaccharide formation [[cite:PUB00066719]]. YjbF is a family of Gram-negative bacterial outer-membrane lipoproteins, predicted to be a beta-barrel and possibly a porin that is one of four gene-products expressed from an operon, yjbEFGH, which is regulated by the Rcs phosphorelay in a RcsA-dependent manner, similar to that of other exopolysaccharide biosynthetic pathways. It is highly possible that the yjbEFGH operon encodes a system involved in EPS secretion since none of the products is predicted to have enzymic activity, the products are all secreted and YbjF and H are predicted to be beta-barrel lipoproteins similar to porins. It may be that the operon products play some role in biofilm formation and/or matrix production [[cite:PUB00066719]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00058168":{"PMID":17379715,"ISBN":null,"volume":"153","issue":"Pt 4","year":2007,"title":"The yjbEFGH locus in Escherichia coli K-12 is an operon encoding proteins involved in exopolysaccharide production.","URL":null,"raw_pages":"1070-80","medline_journal":"Microbiology","ISO_journal":"Microbiology (Reading, Engl.)","authors":["Ferrieres L","Aslam SN","Cooper RM","Clarke DJ."],"DOI_URL":"http://dx.doi.org/10.1099/mic.0.2006/002907-0"},"PUB00099551":{"PMID":21449614,"ISBN":null,"volume":"50","issue":"24","year":2011,"title":"The crystal structure of Escherichia coli group 4 capsule protein GfcC reveals a domain organization resembling that of Wza.","URL":null,"raw_pages":"5465-76","medline_journal":"Biochemistry","ISO_journal":"Biochemistry","authors":["Sathiyamoorthy K","Mills E","Franzmann TM","Rosenshine I","Saper MA."],"DOI_URL":null},"PUB00066719":{"PMID":16030220,"ISBN":null,"volume":"187","issue":"15","year":2005,"title":"Identification of an Escherichia coli operon required for formation of the O-antigen capsule.","URL":null,"raw_pages":"5259-66","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Peleg A","Shifrin Y","Ilan O","Nadler-Yona C","Nov S","Koby S","Baruch K","Altuvia S","Elgrably-Weiss M","Abe CM","Knutton S","Saper MA","Rosenshine I."],"DOI_URL":"http://dx.doi.org/10.1128/JB.187.15.5259-5266.2005"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":1487,"pathways":0,"proteins":1487,"proteomes":1355,"sets":0,"structural_models":{"alphafold":951},"structures":1,"taxa":1884},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":17,"alignment:full":673},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}