{"metadata":{"accession":"PF11080","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR022597","hierarchy":null,"name":{"name":"Endoribonuclease GhoS","short":"GhoS"},"description":[{"text":"<p>GhoS is part of the GhoT-GhoS type V toxin-antitoxin (TA) system. GhoT is inhibited by antitoxin GhoS, which specifically cleaves its  mRNA [[cite:PUB00065335],[cite:PUB00074308]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00065335":{"PMID":22941047,"ISBN":null,"volume":"8","issue":"10","year":2012,"title":"A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS.","URL":null,"raw_pages":"855-61","medline_journal":"Nat Chem Biol","ISO_journal":"Nat. Chem. Biol.","authors":["Wang X","Lord DM","Cheng HY","Osbourne DO","Hong SH","Sanchez-Torres V","Quiroga C","Zheng K","Herrmann T","Peti W","Benedik MJ","Page R","Wood TK."],"DOI_URL":"http://dx.doi.org/10.1038/nchembio.1062"},"PUB00074308":{"PMID":23289863,"ISBN":null,"volume":"15","issue":"6","year":2013,"title":"Type II toxin/antitoxin MqsR/MqsA controls type V toxin/antitoxin GhoT/GhoS.","URL":null,"raw_pages":"1734-44","medline_journal":"Environ Microbiol","ISO_journal":"Environ. Microbiol.","authors":["Wang X","Lord DM","Hong SH","Peti W","Benedik MJ","Page R","Wood TK."],"DOI_URL":"http://dx.doi.org/10.1111/1462-2920.12063"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":322,"pathways":0,"proteins":322,"proteomes":287,"sets":0,"structural_models":{"alphafold":204},"structures":1,"taxa":442},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":4,"alignment:full":99},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}