{"metadata":{"accession":"PF11028","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR021280","hierarchy":null,"name":{"name":"Protein O-mannosyl-transferase TMEM260 N-terminal domain","short":"TMEM260_N"},"description":[{"text":"<p>This entry includes human Protein O-mannosyl-transferase TMEM260 and similar sequences from bacteria and eukaryota. TMEM260 transfers mannosyl residues to the hydroxyl group of serine or threonine residues of proteins [[cite:PUB00151531]]. This entry represents the transmembrane region.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00151531":{"PMID":37186866,"ISBN":null,"volume":"120","issue":"21","year":2023,"title":"The SHDRA syndrome-associated gene <i>TMEM260</i> encodes a protein-specific O-mannosyltransferase.","URL":null,"raw_pages":"e2302584120","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc Natl Acad Sci U S A","authors":["Larsen ISB","Povolo L","Zhou L","Tian W","Mygind KJ","Hintze J","Jiang C","Hartill V","Prescott K","Johnson CA","Mullegama SV","McConkie-Rosell A","McDonald M","Hansen L","Vakhrushev SY","Schjoldager KT","Clausen H","Worzfeld T","Joshi HJ","Halim A."],"DOI_URL":"https://doi.org/10.1073/pnas.2302584120"}},"set_info":{"accession":"CL0111","name":"GT-C"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":24,"interactions":0,"matches":4147,"pathways":0,"proteins":4138,"proteomes":3041,"sets":1,"structural_models":{"alphafold":2994},"structures":0,"taxa":5849},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":70,"alignment:full":2496},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}