{"metadata":{"accession":"PF10882","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR027783","hierarchy":null,"name":{"name":"Bacterial PH domain","short":"bPH_5"},"description":[{"text":"<p>This family of proteins with unknown function appear to be related to bacterial PH domains. This family was formerly known as DUF2679.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Pleckstrin_homology_domain","extract":"<p><b>Pleckstrin homology domain</b> or (<b>PHIP</b>) is a protein domain of approximately 120 amino acids that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton.</p>","thumbnail":null}],"literature":{"PUB00054230":{"PMID":19913036,"ISBN":null,"volume":"396","issue":"1","year":2010,"title":"Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain.","URL":null,"raw_pages":"31-46","medline_journal":"J Mol Biol","ISO_journal":"J. Mol. Biol.","authors":["Xu Q","Bateman A","Finn RD","Abdubek P","Astakhova T","Axelrod HL","Bakolitsa C","Carlton D","Chen C","Chiu HJ","Chiu M","Clayton T","Das D","Deller MC","Duan L","Ellrott K","Ernst D","Farr CL","Feuerhelm J","Grant JC","Grzechnik A","Han GW","Jaroszewski L","Jin KK","Klock HE","Knuth MW","Kozbial P","Krishna SS","Kumar A","Marciano D","McMullan D","Miller MD","Morse AT","Nigoghossian E","Nopakun A","Okach L","Puckett C","Reyes R","Rife CL","Sefcovic N","Tien HJ","Trame CB","van den Bedem H","Weekes D","Wooten T","Hodgson KO","Wooley J","Elsliger MA","Deacon AM","Godzik A","Lesley SA","Wilson IA."],"DOI_URL":"http://dx.doi.org/10.1016/j.jmb.2009.11.006"}},"set_info":{"accession":"CL0266","name":"PH"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":9,"interactions":0,"matches":999,"pathways":0,"proteins":990,"proteomes":916,"sets":1,"structural_models":{"alphafold":643},"structures":0,"taxa":1725},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":16,"alignment:full":557},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}