{"metadata":{"accession":"PF10832","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR022541","hierarchy":null,"name":{"name":"YhfG","short":"YhfG"},"description":[{"text":"<p>This protein family includes proteins predominantly found in Gammaproteobacteria, such as YhfG from Escherichia coli. YhfG is a FicA antitoxin homologue (also known as antitoxin EcFicA) that interacts with EcFiT and forms a complex with it. YhfG shows a unique conformation, forming two parallel alpha- helices linked by a 10-residues loop. The structure of the complex shows a highly conserved extended ligand-binding pocket [[cite:PUB00100669]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00100669":{"PMID":27657533,"ISBN":null,"volume":"11","issue":"9","year":2016,"title":"Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin.","URL":null,"raw_pages":"e0163654","medline_journal":"PLoS One","ISO_journal":"PLoS One","authors":["Stanger FV","Harms A","Dehio C","Schirmer T."],"DOI_URL":null}},"set_info":{"accession":"CL0660","name":"SHOCT"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":537,"pathways":0,"proteins":537,"proteomes":520,"sets":1,"structural_models":{"alphafold":293},"structures":3,"taxa":774},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":20,"alignment:full":117},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"5jff","name":"E. coli EcFicT mutant G55R in complex with EcFicA"}}}