{"metadata":{"accession":"PF10824","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR022536","hierarchy":null,"name":{"name":"Excreted virulence factor EspC, type VII ESX diderm","short":"T7SS_ESX_EspC"},"description":[{"text":"<p>T7SS_ESX-EspC is a family of exported virulence proteins from largely Acinetobacteria and a few Fimicutes, Gram-positive bacteria. It is exported in conjunction with EspA as an interacting pair.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00083131":{"PMID":23541477,"ISBN":null,"volume":"164","issue":"6","year":2013,"title":"Leaving home ain't easy: protein export systems in Gram-positive bacteria.","URL":null,"raw_pages":"664-74","medline_journal":"Res Microbiol","ISO_journal":"Res. Microbiol.","authors":["Freudl R."],"DOI_URL":"http://dx.doi.org/10.1016/j.resmic.2013.03.014"},"PUB00083130":{"PMID":22843727,"ISBN":null,"volume":"287","issue":"38","year":2012,"title":"Specific chaperones for the type VII protein secretion pathway.","URL":null,"raw_pages":"31939-47","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Daleke MH","van der Woude AD","Parret AH","Ummels R","de Groot AM","Watson D","Piersma SR","Jimenez CR","Luirink J","Bitter W","Houben EN."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M112.397596"},"PUB00083129":{"PMID":22140496,"ISBN":null,"volume":"6","issue":"11","year":2011,"title":"Computational analysis of the ESX-1 region of Mycobacterium tuberculosis: insights into the mechanism of type VII secretion system.","URL":null,"raw_pages":"e27980","medline_journal":"PLoS One","ISO_journal":"PLoS ONE","authors":["Das C","Ghosh TS","Mande SS."],"DOI_URL":"http://dx.doi.org/10.1371/journal.pone.0027980"}},"set_info":{"accession":"CL0352","name":"EsxAB"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":10,"interactions":0,"matches":3745,"pathways":0,"proteins":3745,"proteomes":1205,"sets":1,"structural_models":{"alphafold":2406},"structures":0,"taxa":1509},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":17,"alignment:full":1473},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}