{"metadata":{"accession":"PF10794","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR019730","hierarchy":null,"name":{"name":"Protein of unknown function (DUF2606)","short":"DUF2606"},"description":[{"text":"<p>Family of bacterial proteins with unknown function. These proteins have been classified as membrane proteins</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00152278":{"PMID":16220534,"ISBN":null,"volume":"5","issue":"17","year":2005,"title":"Proteomics-based consensus prediction of protein retention in a bacterial membrane.","URL":null,"raw_pages":"4472-82","medline_journal":"Proteomics","ISO_journal":"Proteomics","authors":["Tjalsma H","van Dijl JM."],"DOI_URL":"https://doi.org/10.1002/pmic.200402080"}},"set_info":{"accession":"CL0287","name":"Transthyretin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":31,"pathways":0,"proteins":31,"proteomes":30,"sets":1,"structural_models":{"alphafold":17},"structures":0,"taxa":70},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":9},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}