{"metadata":{"accession":"PF10758","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR019694","hierarchy":null,"name":{"name":"DUF2586, N-terminal domain","short":"DUF2586"},"description":[{"text":"<p>This entry represents the N-terminal domain found in bacterial family of proteins which is a component of a contractile injection system related to phage sheath proteins [[cite:PUB00097484]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00097484":{"PMID":30905475,"ISBN":null,"volume":"177","issue":"2","year":2019,"title":"Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.","URL":null,"raw_pages":"370-383.e15","medline_journal":"Cell","ISO_journal":"Cell","authors":["Jiang F","Li N","Wang X","Cheng J","Huang Y","Yang Y","Yang J","Cai B","Wang YP","Jin Q","Gao N."],"DOI_URL":null}},"set_info":{"accession":"CL0955","name":"TssC1_N-like"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":6,"interactions":0,"matches":683,"pathways":0,"proteins":682,"proteomes":578,"sets":1,"structural_models":{"alphafold":363},"structures":0,"taxa":1112},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":40,"alignment:full":248},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}