{"metadata":{"accession":"PF10476","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR018861","hierarchy":null,"name":{"name":"Protein of unknown function C-terminus (DUF2448)","short":"DUF2448"},"description":[{"text":"<p>The family DUF2349 is the N-terminal part of this family. This protein is found in eukaryotes but its function is not known.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":12,"interactions":0,"matches":973,"pathways":0,"proteins":966,"proteomes":725,"sets":0,"structural_models":{"alphafold":861},"structures":0,"taxa":2242},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":16,"alignment:full":808},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}