{"metadata":{"accession":"PF10340","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR019436","hierarchy":null,"name":{"name":"Steryl acetyl hydrolase","short":"Say1_Mug180"},"description":[{"text":"<p>This entry includes budding yeast steryl acetyl  hydrolase 1 (Say1) and fission yeast Mug180. Say1 is a a membrane-anchored deacetylase  required for the deacetylation of acetylated sterols.   It is involved in the resistance to eugenol and pregnenolone toxicity [[cite:PUB00054134]]. Mug180 has a role in  meiosis [[cite:PUB00044889]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00044889":{"PMID":16303567,"ISBN":null,"volume":"15","issue":"22","year":2005,"title":"A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.","URL":null,"raw_pages":"2056-62","medline_journal":"Curr Biol","ISO_journal":"Curr. Biol.","authors":["Martin-Castellanos C","Blanco M","Rozalen AE","Perez-Hidalgo L","Garcia AI","Conde F","Mata J","Ellermeier C","Davis L","San-Segundo P","Smith GR","Moreno S."],"DOI_URL":"http://dx.doi.org/10.1016/j.cub.2005.10.038"},"PUB00054134":{"PMID":18034159,"ISBN":null,"volume":"26","issue":"24","year":2007,"title":"An acetylation/deacetylation cycle controls the export of sterols and steroids from S. cerevisiae.","URL":null,"raw_pages":"5109-19","medline_journal":"EMBO J","ISO_journal":"EMBO J.","authors":["Tiwari R","Koffel R","Schneiter R."],"DOI_URL":"http://dx.doi.org/10.1038/sj.emboj.7601924"}},"set_info":{"accession":"CL0028","name":"AB_hydrolase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":21,"interactions":0,"matches":551,"pathways":0,"proteins":545,"proteomes":327,"sets":1,"structural_models":{"alphafold":456},"structures":0,"taxa":905},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":5,"alignment:full":402},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}