{"metadata":{"accession":"PF10229","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR019362","hierarchy":null,"name":{"name":"Methylmalonic aciduria and homocystinuria type D protein","short":"MMADHC"},"description":[{"text":"<p>This entry represents methylmalonic aciduria and  homocystinuria type D protein and homologues. These  proteins are involved in cobalamin (vitamin B12)  metabolism [[cite:PUB00059225]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00059225":{"PMID":18385497,"ISBN":null,"volume":"358","issue":"14","year":2008,"title":"Gene identification for the cblD defect of vitamin B12 metabolism.","URL":null,"raw_pages":"1454-64","medline_journal":"N Engl J Med","ISO_journal":"N. Engl. J. Med.","authors":["Coelho D","Suormala T","Stucki M","Lerner-Ellis JP","Rosenblatt DS","Newbold RF","Baumgartner MR","Fowler B."],"DOI_URL":"http://dx.doi.org/10.1056/NEJMoa072200"}},"set_info":{"accession":"CL0529","name":"FMN-dep-NRtase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":44,"interactions":0,"matches":2200,"pathways":0,"proteins":2122,"proteomes":1467,"sets":1,"structural_models":{"alphafold":1852},"structures":5,"taxa":4661},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":17,"alignment:full":1749},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"5cv0","name":"Crystal structure of N-terminal truncated human B12-chaperone CblD (108-296)"}}}