The members of this family function as mitochondrial potassium-hydrogen exchange transporters. The family is part of a large mitochondrial KHE protein complex.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00101048":{"PMID":20197279,"ISBN":null,"volume":"285","issue":"19","year":2010,"title":"Novel components of an active mitochondrial K(+)/H(+) exchange.","URL":null,"raw_pages":"14399-414","medline_journal":"J Biol Chem","ISO_journal":"J Biol Chem","authors":["Zotova L","Aleschko M","Sponder G","Baumgartner R","Reipert S","Prinz M","Schweyen RJ","Nowikovsky K."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":34,"interactions":0,"matches":2266,"pathways":0,"proteins":2233,"proteomes":1846,"sets":0,"structural_models":{"alphafold":1842},"structures":0,"taxa":4180},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":106,"alignment:full":1689},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}