{"metadata":{"accession":"PF10022","entry_id":null,"type":"repeat","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR049349","hierarchy":null,"name":{"name":"Beta-D-glucuronate dehydratase family","short":"BcGHD"},"description":[{"text":"<p>This entry, previously known as DUF2264, represents beta-D-glucuronate dehydratase (BcGHD) from Bacteroides caccae and related proteins. This enzyme primes saturated non-reducing end beta-D-glucuronate residues for hydrolysis by BcGH88 [[cite:PUB00163547]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00163547":{"PMID":40490139,"ISBN":null,"volume":"301","issue":"7","year":2025,"title":"Analysis of chondroitin degradation by components of a Bacteroides caccae polysaccharide utilization locus.","URL":null,"raw_pages":"110354","medline_journal":"J Biol Chem","ISO_journal":"J Biol Chem","authors":["Alvarez B","Canil OF","Low KE","Hettle AG","Abbott DW","Boraston AB."],"DOI_URL":"https://doi.org/10.1016/j.jbc.2025.110354"}},"set_info":{"accession":"CL0059","name":"6_Hairpin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":35,"interactions":0,"matches":5565,"pathways":0,"proteins":5525,"proteomes":3818,"sets":1,"structural_models":{"alphafold":3540},"structures":3,"taxa":5967},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":118,"alignment:full":3178},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"8oi4","name":"Metagenomic Beta-galactosidase from Glycoside Hydrolase family GH154"}}}