{"metadata":{"accession":"PF09982","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR018707","hierarchy":null,"name":{"name":"Outer membrane protein LpxR","short":"LpxR"},"description":[{"text":"<p>The outer membrane protein LpxR from Salmonella typhimurium is a lipid A deacylase that catalyses the removal of the 3'-acyloxyacyl moiety from lipid A. This protein folds into a 12-stranded antiparallel beta-barrel with the N- and C- terminal ends pointing towards the periplasm and three extracellular loops consisting of alpha-helical regions at the opposite side of the beta-barrel [[cite:PUB00051973]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00051973":{"PMID":19174515,"ISBN":null,"volume":"106","issue":"6","year":2009,"title":"Active-site architecture and catalytic mechanism of the lipid A deacylase LpxR of Salmonella typhimurium.","URL":null,"raw_pages":"1960-4","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc. Natl. Acad. Sci. U.S.A.","authors":["Rutten L","Mannie JP","Stead CM","Raetz CR","Reynolds CM","Bonvin AM","Tommassen JP","Egmond MR","Trent MS","Gros P."],"DOI_URL":"http://dx.doi.org/10.1073/pnas.0813064106"}},"set_info":{"accession":"CL0193","name":"MBB"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":2613,"pathways":0,"proteins":2613,"proteomes":2316,"sets":1,"structural_models":{"alphafold":1730},"structures":1,"taxa":3513},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":48,"alignment:full":1283},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"3fid","name":"LpxR from Salmonella typhimurium"}}}