{"metadata":{"accession":"PF09936","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR019230","hierarchy":null,"name":{"name":"SAM-dependent RNA methyltransferase","short":"Methyltrn_RNA_4"},"description":[{"text":"<p>This family has a Rossmanoid fold, with a deep trefoil knot in its C-terminal region. It has structural similarity to RNA methyltransferases, and is likely to function as an S-adenosyl-L-methionine (SAM)-dependent RNA 2'-O methyltransferase [[cite:PUB00051341]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00051341":{"PMID":18831037,"ISBN":null,"volume":"74","issue":"1","year":2009,"title":"Crystal structure of Thermotoga maritima SPOUT superfamily RNA methyltransferase Tm1570 in complex with S-adenosyl-L-methionine.","URL":null,"raw_pages":"245-9","medline_journal":"Proteins","ISO_journal":"Proteins","authors":["Kim do J","Kim HS","Lee SJ","Suh SW."],"DOI_URL":"http://dx.doi.org/10.1002/prot.22249"}},"set_info":{"accession":"CL0098","name":"SPOUT"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":484,"pathways":0,"proteins":484,"proteomes":480,"sets":1,"structural_models":{"alphafold":385},"structures":3,"taxa":1079},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":71,"alignment:full":315},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"3dcm","name":"Crystal structure of the Thermotoga maritima SPOUT family RNA-methyltransferase protein Tm1570 in complex with S-adenosyl-L-methionine"}}}