{"metadata":{"accession":"PF09922","entry_id":null,"type":"repeat","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR024425","hierarchy":null,"name":{"name":"Cell wall-active antibiotics response LiaF, C-terminal","short":"LiaF-like_C"},"description":[{"text":"<p>This domain is found in various prokaryotic proteins, including cell wall-active antibiotic response proteins. This entry includes protein product of the yvqF gene, LiaF, located immediately upstream of vraS. It is associated with glycopeptide resistance in Staphylococcus aureus [[cite:PUB00075646]]. This domain has been described as toast rack from its structural resemblance.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00075647":{"PMID":16923071,"ISBN":null,"volume":"262","issue":"2","year":2006,"title":"The VraS/VraR two-component regulatory system required for oxacillin resistance in community-acquired methicillin-resistant Staphylococcus aureus.","URL":null,"raw_pages":"163-71","medline_journal":"FEMS Microbiol Lett","ISO_journal":"FEMS Microbiol. Lett.","authors":["Boyle-Vavra S","Yin S","Daum RS."],"DOI_URL":"http://dx.doi.org/10.1111/j.1574-6968.2006.00384.x"},"PUB00075646":{"PMID":19889788,"ISBN":null,"volume":"65","issue":"1","year":2010,"title":"Genetic changes associated with glycopeptide resistance in Staphylococcus aureus: predominance of amino acid substitutions in YvqF/VraSR.","URL":null,"raw_pages":"37-45","medline_journal":"J Antimicrob Chemother","ISO_journal":"J. Antimicrob. Chemother.","authors":["Kato Y","Suzuki T","Ida T","Maebashi K."],"DOI_URL":"http://dx.doi.org/10.1093/jac/dkp394"}},"set_info":{"accession":"CL0268","name":"Pec_lyase-like"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":11,"interactions":0,"matches":4805,"pathways":0,"proteins":4805,"proteomes":3793,"sets":1,"structural_models":{"alphafold":2865},"structures":0,"taxa":5007},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":37,"alignment:full":2361},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}