This protein of approx. 100 residues is found in bacteria. It contains up to five alpha helices and up to seven beta strands and is probably monomeric. Its function is unknown. It is cited as a major prophage head protein [[cite:PUB00044231]], so might generally be of viral origin.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00044231":{"PMID":15016546,"ISBN":null,"volume":"320","issue":"2","year":2004,"title":"The prophages of Lactobacillus johnsonii NCC 533: comparative genomics and transcription analysis.","URL":null,"raw_pages":"229-42","medline_journal":"Virology","ISO_journal":"Virology","authors":["Ventura M","Canchaya C","Pridmore RD","Brussow H."],"DOI_URL":"http://dx.doi.org/10.1016/j.virol.2003.11.034"}},"set_info":{"accession":"CL0125","name":"Peptidase_CA"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":127,"pathways":0,"proteins":127,"proteomes":126,"sets":1,"structural_models":{"alphafold":73},"structures":1,"taxa":283},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":34,"alignment:full":41},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"2hly","name":"The crystal structure of genomics APC5867"}}}