{"metadata":{"accession":"PF09594","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR018584","hierarchy":null,"name":{"name":"Glycosyltransferase family 87","short":"GT87"},"description":[{"text":"<p>The enzymes in this family are glycosyltransferases. PimE is involved in phosphatidylinositol mannoside (PIM) synthesis, a major class of glycolipids in all mycobacteria. PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of PIM [[cite:PUB00075385]]. The family also includes alpha(1-->3) arabinofuranosyltransferase, invloved in the synthesis of of mycobacterial arabinogalactan [[cite:PUB00075386]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00075386":{"PMID":18627460,"ISBN":null,"volume":"69","issue":"5","year":2008,"title":"Biosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferase.","URL":null,"raw_pages":"1191-206","medline_journal":"Mol Microbiol","ISO_journal":"Mol. Microbiol.","authors":["Birch HL","Alderwick LJ","Bhatt A","Rittmann D","Krumbach K","Singh A","Bai Y","Lowary TL","Eggeling L","Besra GS."],"DOI_URL":"http://dx.doi.org/10.1111/j.1365-2958.2008.06354.x"},"PUB00075385":{"PMID":16803893,"ISBN":null,"volume":"281","issue":"35","year":2006,"title":"PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of phosphatidylinositol mannoside in mycobacteria.","URL":null,"raw_pages":"25143-55","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Morita YS","Sena CB","Waller RF","Kurokawa K","Sernee MF","Nakatani F","Haites RE","Billman-Jacobe H","McConville MJ","Maeda Y","Kinoshita T."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M604214200"}},"set_info":{"accession":"CL0111","name":"GT-C"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":44,"interactions":0,"matches":16183,"pathways":0,"proteins":16098,"proteomes":5451,"sets":1,"structural_models":{"alphafold":9401},"structures":3,"taxa":7478},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":76,"alignment:full":7692},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}