{"metadata":{"accession":"PF09209","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR015292","hierarchy":null,"name":{"name":"HTH-type transcriptional dual regulator CecR, C-terminal domain","short":"CecR_C"},"description":[{"text":"<p>This entry represents the C-terminal domain found in CecR (regulator  of cefoperazone and chloramphenicol sensitivity), previously known  as YbiH. CecR has been shown to control sensitivity to cefoperazone  and chloramphenicol through regulating the transcription of the  cecR-ybhGFSR operon and the rhlE gene [[cite:PUB00104740]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00104740":{"PMID":27112147,"ISBN":null,"volume":"162","issue":"7","year":2016,"title":"Transcription factor CecR (YbiH) regulates a set of genes affecting the sensitivity of Escherichia coli against cefoperazone and chloramphenicol.","URL":null,"raw_pages":"1253-1264","medline_journal":"Microbiology (Reading)","ISO_journal":"Microbiology (Reading)","authors":["Yamanaka Y","Shimada T","Yamamoto K","Ishihama A."],"DOI_URL":null}},"set_info":{"accession":"CL0174","name":"TetR_C"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":5,"interactions":0,"matches":2047,"pathways":0,"proteins":2046,"proteomes":1822,"sets":1,"structural_models":{"alphafold":1312},"structures":4,"taxa":2903},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":24,"alignment:full":924},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"9i1x","name":"Crystal structure of the E. coli TetR family regulator CecR"}}}