Members of this family of Mycoplasma hypothetical proteins adopt a helical structure, with one central alpha-helix surrounded by five others, in a NusB-like fold. Their function has not, as yet, been determined [[cite:PUB00030162]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00030162":{"PMID":15146506,"ISBN":null,"volume":"55","issue":"4","year":2004,"title":"A conserved hypothetical protein from Mycoplasma genitalium shows structural homology to nusb proteins.","URL":null,"raw_pages":"1082-6","medline_journal":"Proteins","ISO_journal":"Proteins","authors":["Liu J","Yokota H","Kim R","Kim SH."],"DOI_URL":"http://dx.doi.org/10.1002/prot.20119"}},"set_info":{"accession":"CL0633","name":"NusB"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":3,"pathways":0,"proteins":3,"proteomes":3,"sets":1,"structural_models":{"alphafold":3},"structures":1,"taxa":18},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":3},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"1q8c","name":"A conserved hypothetical protein from Mycoplasma genitalium shows structural homology to NusB proteins"}}}