Members of this family are found in maltosyltransferases, and adopt a secondary structure consisting of eight antiparallel beta-strands, which form an open-sided 'jelly roll' Greek key beta-barrel. Their exact function is, as yet, unknown [[cite:PUB00025274]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00025274":{"PMID":11545590,"ISBN":null,"volume":"312","issue":"1","year":2001,"title":"The crystal structure of Thermotoga maritima maltosyltransferase and its implications for the molecular basis of the novel transfer specificity.","URL":null,"raw_pages":"119-31","medline_journal":"J Mol Biol","ISO_journal":"J. Mol. Biol.","authors":["Roujeinikova A","Raasch C","Burke J","Baker PJ","Liebl W","Rice DW."],"DOI_URL":"http://dx.doi.org/10.1006/jmbi.2001.4944"}},"set_info":{"accession":"CL0369","name":"GHD"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":5,"pathways":0,"proteins":5,"proteomes":4,"sets":1,"structural_models":{"alphafold":5},"structures":2,"taxa":16},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":1,"alignment:full":1},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}