{"metadata":{"accession":"PF08907","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR015003","hierarchy":null,"name":{"name":"Domain of unknown function (DUF1853)","short":"DUF1853"},"description":[{"text":"<p>This family of proteins are functionally uncharacterised.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00066699":{"PMID":22638584,"ISBN":null,"volume":"40","issue":"15","year":2012,"title":"Sequence, structure and functional diversity of PD-(D/E)XK phosphodiesterase superfamily.","URL":null,"raw_pages":"7016-45","medline_journal":"Nucleic Acids Res","ISO_journal":"Nucleic Acids Res.","authors":["Steczkiewicz K","Muszewska A","Knizewski L","Rychlewski L","Ginalski K."],"DOI_URL":"http://dx.doi.org/10.1093/nar/gks382"}},"set_info":{"accession":"CL0236","name":"PDDEXK"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":15,"interactions":0,"matches":2391,"pathways":0,"proteins":2376,"proteomes":2328,"sets":1,"structural_models":{"alphafold":1432},"structures":0,"taxa":3134},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":20,"alignment:full":922},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}