{"metadata":{"accession":"PF08759","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR014869","hierarchy":null,"name":{"name":"Glycosyltransferase GT-D fold","short":"GT-D"},"description":[{"text":"<p>This domain is found at the C terminus of proteins such as the probable glycosyltransferase Gly ([swissprot:Q9AEU2]) that also contain the glycosyl transferase domain at the N terminus. It is also found N-terminal in numerous putative glycosyltransferases such as GalT1. GalT1 has been shown to catalyse the third step of Fap1  glycosylation [[cite:PUB00081880]]. This domain is structurally distinct from all known GT folds of glycosyltransferases and contains a metal binding site. This new glycosyltransferase fold has been named GT-D [[cite:PUB00081880]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00081880":{"PMID":25023666,"ISBN":null,"volume":"5","issue":null,"year":2014,"title":"The highly conserved domain of unknown function 1792 has a distinct glycosyltransferase fold.","URL":null,"raw_pages":"4339","medline_journal":"Nat Commun","ISO_journal":"Nat Commun","authors":["Zhang H","Zhu F","Yang T","Ding L","Zhou M","Li J","Haslam SM","Dell A","Erlandsen H","Wu H."],"DOI_URL":"http://dx.doi.org/10.1038/ncomms5339"}},"set_info":{"accession":"CL0818","name":"GT-D-like"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":21,"interactions":0,"matches":343,"pathways":0,"proteins":343,"proteomes":310,"sets":1,"structural_models":{"alphafold":198},"structures":4,"taxa":665},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":8,"alignment:full":171},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"5v4a","name":"A New Glycosyltransferase (DUF1792) from Streptococcus sanguinis"}}}