{"metadata":{"accession":"PF08747","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR014858","hierarchy":null,"name":{"name":"BREX protein BrxB","short":"BrxB"},"description":[{"text":"<p>This family includes BREX protein BrxB from Bacillus cereus, which is part of a type 1 BREX (bacteriophage exclusion) system, a system that provides immunity against bacteriophage, which allows phage adsorption but prevents phage DNA replication, without degradation of the phage DNA [[cite:PUB00093365]]. The exact function of BrxB is not clear.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00093365":{"PMID":25452498,"ISBN":null,"volume":"34","issue":"2","year":2015,"title":"BREX is a novel phage resistance system widespread in microbial genomes.","URL":null,"raw_pages":"169-83","medline_journal":"EMBO J","ISO_journal":"EMBO J.","authors":["Goldfarb T","Sberro H","Weinstock E","Cohen O","Doron S","Charpak-Amikam Y","Afik S","Ofir G","Sorek R."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":1196,"pathways":0,"proteins":1196,"proteomes":1121,"sets":0,"structural_models":{"alphafold":819},"structures":3,"taxa":2516},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":36,"alignment:full":623},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}