{"metadata":{"accession":"PF08745","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR014856","hierarchy":null,"name":{"name":"PINc domain ribonuclease","short":"PIN_5"},"description":[{"text":"<p>This is a family of bacterial and archaeal PINc domains. PIN domains are characterised by the conservation of three acidic residues, possibly four, an Asp at residue 13, a Glu at 63, and then Asps at 172 and 194 in UniProtKB:Q58360. Family members include Homologs of Aquifex RNase P (HARP) proteins [[cite:PUB00091006]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00091006":{"PMID":28575517,"ISBN":null,"volume":"45","issue":"12","year":2017,"title":"Comprehensive classification of the PIN domain-like superfamily.","URL":null,"raw_pages":"6995-7020","medline_journal":"Nucleic Acids Res","ISO_journal":"Nucleic Acids Res.","authors":["Matelska D","Steczkiewicz K","Ginalski K."],"DOI_URL":"https://doi.org/10.1093/nar/gkx494"},"PUB00059173":{"PMID":21036780,"ISBN":null,"volume":"24","issue":"1-2","year":2011,"title":"The PIN-domain ribonucleases and the prokaryotic VapBC toxin-antitoxin array.","URL":null,"raw_pages":"33-40","medline_journal":"Protein Eng Des Sel","ISO_journal":"Protein Eng. Des. Sel.","authors":["Arcus VL","McKenzie JL","Robson J","Cook GM."],"DOI_URL":"http://dx.doi.org/10.1093/protein/gzq081"}},"set_info":{"accession":"CL0280","name":"PIN"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":328,"pathways":0,"proteins":328,"proteomes":322,"sets":1,"structural_models":{"alphafold":306},"structures":9,"taxa":664},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":31,"alignment:full":140},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}