This is a fungal family of unknown function. One of the proteins in this family [swissprot:P32792] has been localised to the mitochondria [[cite:PUB00033287]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00033287":{"PMID":14576278,"ISBN":null,"volume":"100","issue":"23","year":2003,"title":"The proteome of Saccharomyces cerevisiae mitochondria.","URL":null,"raw_pages":"13207-12","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc. Natl. Acad. Sci. U.S.A.","authors":["Sickmann A","Reinders J","Wagner Y","Joppich C","Zahedi R","Meyer HE","Schonfisch B","Perschil I","Chacinska A","Guiard B","Rehling P","Pfanner N","Meisinger C."],"DOI_URL":"http://dx.doi.org/10.1073/pnas.2135385100"}},"set_info":{"accession":"CL0063","name":"NADP_Rossmann"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":24,"interactions":0,"matches":1309,"pathways":0,"proteins":1243,"proteomes":1207,"sets":1,"structural_models":{"alphafold":1031},"structures":0,"taxa":2495},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":13,"alignment:full":1047},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}