{"metadata":{"accession":"PF08583","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR013892","hierarchy":null,"name":{"name":"Cytochrome c oxidase biogenesis protein Cmc1 like","short":"Cmc1"},"description":[{"text":"<p>Cmc1 is a metallo-chaperone like protein which is known to localise to the inner mitochondrial membrane in Saccharomyces cerevisiae.  It is essential for full expression of cytochrome c oxidase and respiration [[cite:PUB00044676]].  Cmc1 contains two Cx9C motifs and is able to bind copper(I).  Cmc1 is thought to play a role in mitochondrial copper trafficking and transfer to cytochrome c oxidase [[cite:PUB00044676]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00044676":{"PMID":18443040,"ISBN":null,"volume":"28","issue":"13","year":2008,"title":"Cmc1p is a conserved mitochondrial twin CX9C protein involved in cytochrome c oxidase biogenesis.","URL":null,"raw_pages":"4354-64","medline_journal":"Mol Cell Biol","ISO_journal":"Mol. Cell. Biol.","authors":["Horn D","Al-Ali H","Barrientos A."],"DOI_URL":"http://dx.doi.org/10.1128/MCB.01920-07"}},"set_info":{"accession":"CL0351","name":"CHCH"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":81,"interactions":0,"matches":6771,"pathways":0,"proteins":6753,"proteomes":3205,"sets":1,"structural_models":{"alphafold":5817},"structures":3,"taxa":8526},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":46,"alignment:full":5212},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}