{"metadata":{"accession":"PF08550","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR013860","hierarchy":null,"name":{"name":"Nitrogen regulatory protein areA, GATA-like domain","short":"GATA_AreA"},"description":[{"text":"<p>This entry represents fungal proteins containing GATA domains, including nitrogen regulatory protein areA, a transcription activator that binds the consensus DNA element 5'-CGATAG-3' and mediates nitrogen metabolite repression [[cite:PUB00089490]]. This entry also contains the Negative regulator of RAS-cAMP pathway MKS1 from yeast that is thought to be a negative regulator of RAS-cAMP pathway.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00089490":{"PMID":1970293,"ISBN":null,"volume":"9","issue":"5","year":1990,"title":"The regulatory gene areA mediating nitrogen metabolite repression in Aspergillus nidulans. Mutations affecting specificity of gene activation alter a loop residue of a putative zinc finger.","URL":null,"raw_pages":"1355-64","medline_journal":"EMBO J","ISO_journal":"EMBO J.","authors":["Kudla B","Caddick MX","Langdon T","Martinez-Rossi NM","Bennett CF","Sibley S","Davies RW","Arst HN Jr."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":81,"interactions":0,"matches":5331,"pathways":0,"proteins":5330,"proteomes":1559,"sets":0,"structural_models":{"alphafold":4349},"structures":0,"taxa":3362},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":121,"alignment:full":4387},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}