{"metadata":{"accession":"PF08522","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR013728","hierarchy":null,"name":{"name":"BT_3987-like, N-terminal domain","short":"BT_3987-like_N"},"description":[{"text":"<p>This domain, previously known as DUF1735, is found in a number of proteins mainly found in firmicutes, including BT_3987 from Bacteroides thetaiotaomicron, which displays hydrolytic activity against Hy-type N-glycans, probably initiating the degradation of this type of glycan in the human gut [[cite:PUB00152803]]. This domain adopts a beta-sandwich fold.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00152803":{"PMID":34324829,"ISBN":null,"volume":"297","issue":"2","year":2021,"title":"GH18 endo-β-N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans.","URL":null,"raw_pages":"101011","medline_journal":"J Biol Chem","ISO_journal":"J Biol Chem","authors":["Trastoy B","Du JJ","Li C","Garcia-Alija M","Klontz EH","Roberts BR","Donahue TC","Wang LX","Sundberg EJ","Guerin ME."],"DOI_URL":"https://doi.org/10.1016/j.jbc.2021.101011"},"PUB00152802":{"PMID":34420703,"ISBN":null,"volume":"272","issue":null,"year":2021,"title":"Discrete genetic loci in human gut Bacteroides thetaiotaomicron confer pectin metabolism.","URL":null,"raw_pages":"118534","medline_journal":"Carbohydr Polym","ISO_journal":"Carbohydr Polym","authors":["Li M","Li S","Guo X","Guo C","Wang Y","Du Z","Zhang Z","Xie C","Ding K."],"DOI_URL":"https://doi.org/10.1016/j.carbpol.2021.118534"}},"set_info":{"accession":"CL0159","name":"E-set"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":41,"interactions":0,"matches":2082,"pathways":0,"proteins":1935,"proteomes":711,"sets":1,"structural_models":{"alphafold":1291},"structures":12,"taxa":1049},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":90,"alignment:full":1119},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}