{"metadata":{"accession":"PF08340","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR013551","hierarchy":null,"name":{"name":"Endoribonuclease YicC-like, C-terminal","short":"YicC-like_C"},"description":[{"text":"<p>This domain is found at the C-terminal end of Endoribonuclease YicC from Escherichia coli and similar bacterial sequences. YicC, which is important for cells in the stationary phase, and essential for growth at high temperatures [[cite:PUB00020576]], contributes to degradation of the small RNA (sRNA) RhyB via collaboration with the exoribonuclease PNPase [[cite:PUB00151089]] and seems to generate a 3'-OH and a 5'-phosphate group [[cite:PUB00151088]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00020576":{"PMID":1925027,"ISBN":null,"volume":"142","issue":"2-3","year":1991,"title":"Three genes preceding pyrE on the Escherichia coli chromosome are essential for survival and normal cell morphology in stationary culture and at high temperature.","URL":null,"raw_pages":"283-8","medline_journal":"Res Microbiol","ISO_journal":"Res. Microbiol.","authors":["Poulsen P","Jensen KF."],"DOI_URL":"http://dx.doi.org/10.1016/0923-2508(91)90042-9"},"PUB00151088":{"PMID":34815358,"ISBN":null,"volume":"28","issue":"2","year":2022,"title":"Discovery and initial characterization of YloC, a novel endoribonuclease in <i>Bacillus subtilis</i>.","URL":null,"raw_pages":"227-238","medline_journal":"RNA","ISO_journal":"RNA","authors":["Ingle S","Chhabra S","Chen J","Lazarus MB","Luo X","Bechhofer DH."],"DOI_URL":null},"PUB00151089":{"PMID":34210798,"ISBN":null,"volume":"118","issue":"27","year":2021,"title":"A fluorescence-based genetic screen reveals diverse mechanisms silencing small RNA signaling in E. coli. ","URL":null,"raw_pages":"e2106964118","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc Natl Acad Sci U S A","authors":["Chen J","To L","de Mets F","Luo X","Majdalani N","Tai CH","Gottesman S."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":9,"interactions":0,"matches":10754,"pathways":0,"proteins":10738,"proteomes":10713,"sets":0,"structural_models":{"alphafold":7104},"structures":3,"taxa":15420},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":254,"alignment:full":5570},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}