{"metadata":{"accession":"PF08331","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR013542","hierarchy":null,"name":{"name":"Epoxyqueuosine reductase QueG, DUF1730","short":"QueG_DUF1730"},"description":[{"text":"<p>This domain of unknown function occurs in Epoxyqueuosine reductase QueG, an iron-sulfur cluster-binding protein, together with the 4Fe-4S binding domain ([pfam:PF00037]). QueG catalyses the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) [[cite:PUB00058202]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00058202":{"PMID":21502530,"ISBN":null,"volume":"108","issue":"18","year":2011,"title":"Discovery of epoxyqueuosine (oQ) reductase reveals parallels between halorespiration and tRNA modification.","URL":null,"raw_pages":"7368-72","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc. Natl. Acad. Sci. U.S.A.","authors":["Miles ZD","McCarty RM","Molnar G","Bandarian V."],"DOI_URL":"http://dx.doi.org/10.1073/pnas.1018636108"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":17,"interactions":0,"matches":10771,"pathways":0,"proteins":10770,"proteomes":10737,"sets":0,"structural_models":{"alphafold":6905},"structures":5,"taxa":15247},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":277,"alignment:full":5396},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}