{"metadata":{"accession":"PF08226","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR013182","hierarchy":null,"name":{"name":"Domain of unknown function (DUF1720)","short":"DUF1720"},"description":[{"text":"<p>This domain is found in different combinations with cortical patch components EF hand, SH3 and ENTH and is therefore likely to be involved in cytoskeletal processes.  This family contains many hypothetical proteins.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":113,"interactions":0,"matches":1877,"pathways":0,"proteins":1675,"proteomes":1014,"sets":0,"structural_models":{"alphafold":826},"structures":0,"taxa":2308},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":63,"alignment:full":1601},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}