{"metadata":{"accession":"PF08101","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR012965","hierarchy":null,"name":{"name":"Meiotically up-regulated protein Msb1/Mug8 domain","short":"Msb1-Mug8_dom"},"description":[{"text":"<p>This domain of unknown function is found in fungal proteins including Mug8 from Schizosaccharomyces pombe which may have a role in meiosis and septation [[cite:PUB00044889]]. Saccharomyces cerevisiae homologue MSB1 (swiss:P21339) may be involved in positive regulation of 1,3-beta-glucan synthesis and the Pkc1p-MAPK pathway [[cite:PUB00087082]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00044889":{"PMID":16303567,"ISBN":null,"volume":"15","issue":"22","year":2005,"title":"A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.","URL":null,"raw_pages":"2056-62","medline_journal":"Curr Biol","ISO_journal":"Curr. Biol.","authors":["Martin-Castellanos C","Blanco M","Rozalen AE","Perez-Hidalgo L","Garcia AI","Conde F","Mata J","Ellermeier C","Davis L","San-Segundo P","Smith GR","Moreno S."],"DOI_URL":"http://dx.doi.org/10.1016/j.cub.2005.10.038"},"PUB00087082":{"PMID":12399379,"ISBN":null,"volume":"162","issue":"2","year":2002,"title":"Dissection of upstream regulatory components of the Rho1p effector, 1,3-beta-glucan synthase, in Saccharomyces cerevisiae.","URL":null,"raw_pages":"663-76","medline_journal":"Genetics","ISO_journal":"Genetics","authors":["Sekiya-Kawasaki M","Abe M","Saka A","Watanabe D","Kono K","Minemura-Asakawa M","Ishihara S","Watanabe T","Ohya Y."],"DOI_URL":null}},"set_info":{"accession":"CL0409","name":"GAP"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":26,"interactions":0,"matches":1703,"pathways":0,"proteins":1692,"proteomes":1349,"sets":1,"structural_models":{"alphafold":1176},"structures":0,"taxa":2781},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":62,"alignment:full":1345},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}