{"metadata":{"accession":"PF07954","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR012470","hierarchy":null,"name":{"name":"Protein of unknown function (DUF1689)","short":"DUF1689"},"description":[{"text":"<p>Family of fungal proteins with unknown function. A member of this family has been found to localise in the  mitochondria [[cite:PUB00016470]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00016470":{"PMID":14562095,"ISBN":null,"volume":"425","issue":"6959","year":2003,"title":"Global analysis of protein localization in budding yeast.","URL":null,"raw_pages":"686-91","medline_journal":"Nature","ISO_journal":"Nature","authors":["Huh WK","Falvo JV","Gerke LC","Carroll AS","Howson RW","Weissman JS","O'Shea EK."],"DOI_URL":"http://dx.doi.org/10.1038/nature02026"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":164,"pathways":0,"proteins":164,"proteomes":136,"sets":0,"structural_models":{"alphafold":137},"structures":0,"taxa":290},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":33,"alignment:full":108},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}