{"metadata":{"accession":"PF07944","entry_id":null,"type":"repeat","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR012878","hierarchy":null,"name":{"name":"Beta-L-arabinofuranosidase, GH127 catalytic domain","short":"Beta-AFase-like_GH127_cat"},"description":[{"text":"<p>This entry represents the catalytic domain of Non-reducing end beta-L-arabinofuranosidase from Bifidobacterium longum (Beta -AFase) and similar proteins that belong to the glycoside hydrolase family 127 (GH127). This domain folds into an (alpha /alpha)6 barrel. Beta-AFase has been characterised as an unusual beta-L-arabinofuranosidase enzyme, [ec:3.2.1.185]. It releases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration [[cite:PUB00075450],[cite:PUB00151606]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00151606":{"PMID":24680821,"ISBN":null,"volume":"447","issue":"1","year":2014,"title":"Crystal structure of glycoside hydrolase family 127 β-l-arabinofuranosidase from Bifidobacterium longum.","URL":null,"raw_pages":"32-7","medline_journal":"Biochem Biophys Res Commun","ISO_journal":"Biochem Biophys Res Commun","authors":["Ito T","Saikawa K","Kim S","Fujita K","Ishiwata A","Kaeothip S","Arakawa T","Wakagi T","Beckham GT","Ito Y","Fushinobu S."],"DOI_URL":null},"PUB00075450":{"PMID":24385433,"ISBN":null,"volume":"289","issue":"8","year":2014,"title":"Characterization of a novel β-L-arabinofuranosidase in Bifidobacterium longum: functional elucidation of a DUF1680 protein family member.","URL":null,"raw_pages":"5240-9","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Fujita K","Takashi Y","Obuchi E","Kitahara K","Suganuma T."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M113.528711"}},"set_info":{"accession":"CL0059","name":"6_Hairpin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":263,"interactions":0,"matches":12991,"pathways":0,"proteins":12425,"proteomes":5607,"sets":1,"structural_models":{"alphafold":8038},"structures":20,"taxa":9109},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":18,"alignment:full":7126},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"8k7y","name":"Crystal structure of GH146 beta-L-arabinofuranosidase Bll3HypBA1 (amino acids 380-1051), ligand-free form"}}}