This is a family of proteins of unknown function expressed by various bacterial species. Some members of this family (e.g. [swissprot:Q8Z8Z7], [swissprot:Q8ZRF4]) are thought to be lipoproteins. Another member of this family ([swissprot:Q93SV8]) is thought to be involved in photosynthesis [[cite:PUB00015226]]. Based on structure predictions (from AlphaFold and structural comparisons using DALI server), this family may have a lysozyme-like fold.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00015226":{"PMID":10976061,"ISBN":null,"volume":"289","issue":"5485","year":2000,"title":"Molecular evidence for the early evolution of photosynthesis.","URL":null,"raw_pages":"1724-30","medline_journal":"Science","ISO_journal":"Science","authors":["Xiong J","Fischer WM","Inoue K","Nakahara M","Bauer CE."],"DOI_URL":"http://dx.doi.org/10.1126/science.289.5485.1724"}},"set_info":{"accession":"CL0037","name":"Lysozyme"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":1214,"pathways":0,"proteins":1213,"proteomes":1186,"sets":1,"structural_models":{"alphafold":665},"structures":0,"taxa":1593},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":20,"alignment:full":324},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}