Archaeal S-layer proteins consist of two copies of this domain [[cite:PUB00060425],[cite:PUB00152243]].
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Methanosarcinales_S-layer_Tile_Protein","extract":"The Methanosarcinales S-layer Tile Protein (MSTP) is a protein family found almost exclusively in Methanomicrobia members of the order Methanosarcinales. Typically a tandem repeat of two DUF1608 domains are contained in a single MSTP protein chain and these proteins self-assemble into the protective proteinaceous surface layer (S-layer) structure that encompasses the cell. The S-layer, which is found in most Archaea, and in many bacteria, serves many crucial functions including protection from deleterious extracellular substances.
","thumbnail":null}],"literature":{"PUB00152243":{"PMID":22666082,"ISBN":null,"volume":"2012","issue":null,"year":2012,"title":"Identification of the major expressed S-layer and cell surface-layer-related proteins in the model methanogenic archaea: Methanosarcina barkeri Fusaro and Methanosarcina acetivorans C2A.","URL":null,"raw_pages":"873589","medline_journal":"Archaea","ISO_journal":"Archaea","authors":["Rohlin L","Leon DR","Kim U","Loo JA","Ogorzalek Loo RR","Gunsalus RP."],"DOI_URL":"https://doi.org/10.1155/2012/873589"},"PUB00060425":{"PMID":19228054,"ISBN":null,"volume":"8","issue":"4","year":2009,"title":"S-layer, surface-accessible, and concanavalin A binding proteins of Methanosarcina acetivorans and Methanosarcina mazei.","URL":null,"raw_pages":"1972-82","medline_journal":"J Proteome Res","ISO_journal":"J. Proteome Res.","authors":["Francoleon DR","Boontheung P","Yang Y","Kin U","Ytterberg AJ","Denny PA","Denny PC","Loo JA","Gunsalus RP","Loo RR."],"DOI_URL":"http://dx.doi.org/10.1021/pr800923e"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":45,"interactions":0,"matches":606,"pathways":0,"proteins":336,"proteomes":51,"sets":0,"structural_models":{"alphafold":273},"structures":2,"taxa":96},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":38,"alignment:full":175},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}