{"metadata":{"accession":"PF07591","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":null,"hierarchy":null,"name":{"name":"Pretoxin HINT domain","short":"PT-HINT"},"description":[{"text":"<p>A member of the HINT superfamily of proteases that is usually found N-terminal to the toxin module in polymorphic toxin systems. The  domain is predicted to function in releasing the toxin domain by  autoproteolysis [[cite:PUB00057479]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00057479":{"PMID":21306995,"ISBN":null,"volume":"39","issue":"11","year":2011,"title":"A novel immunity system for bacterial nucleic acid degrading toxins and its recruitment in various eukaryotic and DNA viral systems.","URL":null,"raw_pages":"4532-52","medline_journal":"Nucleic Acids Res","ISO_journal":"Nucleic Acids Res.","authors":["Zhang D","Iyer LM","Aravind L."],"DOI_URL":"http://dx.doi.org/10.1093/nar/gkr036"}},"set_info":{"accession":"CL0363","name":"H-int"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1049,"interactions":0,"matches":4640,"pathways":0,"proteins":4593,"proteomes":2065,"sets":1,"structural_models":{"alphafold":1207},"structures":3,"taxa":3206},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":3,"alignment:full":2237},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}