{"metadata":{"accession":"PF07336","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR010852","hierarchy":null,"name":{"name":"Putative stress-induced transcription regulator","short":"ABATE"},"description":[{"text":"<p>The structure of one member of the ABATE domain family consists of a two-domain organisation, with the N-terminal domain presenting a new fold called the ABATE domain that may bind an as yet unknown ligand. The C-terminal domain forms a treble-clef zinc-finger that is likely to be involved in DNA binding. suggests a role as stress-induced transcriptional regulator. Further computational analyses sugeests a role as a stress-induced transcriptional regulator [[cite:PUB00054176]]. Members of this family are found in Streptomyces, Rhizobium, Ralstonia, Agrobacterium and Bradyrhizobium species.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00054176":{"PMID":20944211,"ISBN":null,"volume":"66","issue":"Pt 10","year":2010,"title":"The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45 A resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator.","URL":null,"raw_pages":"1198-204","medline_journal":"Acta Crystallogr Sect F Struct Biol Cryst Commun","ISO_journal":"Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.","authors":["Bakolitsa C","Bateman A","Jin KK","McMullan D","Krishna SS","Miller MD","Abdubek P","Acosta C","Astakhova T","Axelrod HL","Burra P","Carlton D","Chiu HJ","Clayton T","Das D","Deller MC","Duan L","Elias Y","Feuerhelm J","Grant JC","Grzechnik A","Grzechnik SK","Han GW","Jaroszewski L","Klock HE","Knuth MW","Kozbial P","Kumar A","Marciano D","Morse AT","Murphy KD","Nigoghossian E","Okach L","Oommachen S","Paulsen J","Reyes R","Rife CL","Sefcovic N","Tien H","Trame CB","Trout CV","van den Bedem H","Weekes D","White A","Xu Q","Hodgson KO","Wooley J","Elsliger MA","Deacon AM","Godzik A","Lesley S","Wilson IA."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":13,"interactions":0,"matches":14369,"pathways":0,"proteins":14367,"proteomes":4402,"sets":0,"structural_models":{"alphafold":7669},"structures":1,"taxa":5652},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":187,"alignment:full":6392},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"3h0n","name":"Crystal structure of a duf1470 family protein (jann_2411) from jannaschia sp. ccs1 at 1.45 A resolution"}}}