{"metadata":{"accession":"PF07332","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009937","hierarchy":null,"name":{"name":"Putative Actinobacterial Holin-X, holin superfamily III","short":"Phage_holin_3_6"},"description":[{"text":"<p>Phage_holin_3_6 is a family of small hydrophobic proteins with two or three transmembrane domains of the Hol-X family. Holin proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":8,"interactions":0,"matches":12685,"pathways":0,"proteins":12683,"proteomes":8591,"sets":0,"structural_models":{"alphafold":7594},"structures":0,"taxa":11222},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":224,"alignment:full":5946},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}