{"metadata":{"accession":"PF07165","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009832","hierarchy":null,"name":{"name":"Protein of unknown function (DUF1397)","short":"DUF1397"},"description":[{"text":"<p>This family consists of several insect specific proteins. [swissprot:Q25513] is annotated as being a haemolymph glycoprotein precursor. The function of this family is unknown [[cite:PUB00013024]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00013024":{"PMID":7742978,"ISBN":null,"volume":"4","issue":"1","year":1995,"title":"Isolation, cloning and deduced amino acid sequence of a novel glycoprotein from the haemolymph of the hawkmoth Manduca sexta.","URL":null,"raw_pages":"7-13","medline_journal":"Insect Mol Biol","ISO_journal":"Insect Mol. Biol.","authors":["Samaraweera P","Law JH."],"DOI_URL":"http://dx.doi.org/10.1111/j.1365-2583.1995.tb00002.x"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":17,"interactions":0,"matches":888,"pathways":0,"proteins":868,"proteomes":273,"sets":0,"structural_models":{"alphafold":739},"structures":0,"taxa":1101},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":33,"alignment:full":492},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}