This family consists of several Trypanosoma brucei putative variant specific antigen proteins of around 80 residues in length.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00019451":{"PMID":9763292,"ISBN":null,"volume":"95","issue":"1","year":1998,"title":"Selection for activation of a new variant surface glycoprotein gene expression site in Trypanosoma brucei can result in deletion of the old one.","URL":null,"raw_pages":"97-109","medline_journal":"Mol Biochem Parasitol","ISO_journal":"Mol. Biochem. Parasitol.","authors":["Rudenko G","Chaves I","Dirks-Mulder A","Borst P."],"DOI_URL":"http://dx.doi.org/10.1016/S0166-6851(98)00099-1"},"PUB00019452":{"PMID":2720787,"ISBN":null,"volume":"57","issue":"5","year":1989,"title":"The genes and transcripts of an antigen gene expression site from T. brucei.","URL":null,"raw_pages":"835-45","medline_journal":"Cell","ISO_journal":"Cell","authors":["Pays E","Tebabi P","Pays A","Coquelet H","Revelard P","Salmon D","Steinert M."],"DOI_URL":"http://dx.doi.org/10.1016/0092-8674(89)90798-8"},"PUB00019453":{"PMID":3405209,"ISBN":null,"volume":"8","issue":"6","year":1988,"title":"Putative genes of a variant-specific antigen gene transcription unit in Trypanosoma brucei.","URL":null,"raw_pages":"2367-78","medline_journal":"Mol Cell Biol","ISO_journal":"Mol. Cell. Biol.","authors":["Alexandre S","Guyaux M","Murphy NB","Coquelet H","Pays A","Steinert M","Pays E."],"DOI_URL":"http://mcb.asm.org/cgi/content/abstract/8/6/2367"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":6,"pathways":0,"proteins":6,"proteomes":0,"sets":0,"structural_models":{"alphafold":6},"structures":0,"taxa":13},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":0},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}