{"metadata":{"accession":"PF07077","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009781","hierarchy":null,"name":{"name":"Virulence factor BPSS1818","short":"BPSS1818"},"description":[{"text":"<p>This entry (ex DUF1345) represents BPSS1818, a virulence factor required for full Burkholderia pseudomallei pathogenesis in vivo. BPSS1818 is involved in indirect modulation of mammalian host cell tubulin, probably in concert with other bacterial components [[cite:PUB00159059]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00159059":{"PMID":33772012,"ISBN":null,"volume":"12","issue":"1","year":2021,"title":"The Burkholderia pseudomallei intracellular 'TRANSITome'.","URL":null,"raw_pages":"1907","medline_journal":"Nat Commun","ISO_journal":"Nat Commun","authors":["Heacock-Kang Y","McMillan IA","Norris MH","Sun Z","Zarzycki-Siek J","Bluhm AP","Cabanas D","Norton RE","Ketheesan N","Miller JF","Schweizer HP","Hoang TT."],"DOI_URL":"https://doi.org/10.1038/s41467-021-22169-1"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":4178,"pathways":0,"proteins":4176,"proteomes":3794,"sets":0,"structural_models":{"alphafold":2549},"structures":0,"taxa":5000},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":88,"alignment:full":1890},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}