{"metadata":{"accession":"PF06973","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009720","hierarchy":null,"name":{"name":"Domain of unknown function (DUF1297)","short":"DUF1297"},"description":[{"text":"<p>This family represents the C-terminus (approximately 200 residues) of a number of archaeal proteins of unknown function. One member is annotated as being a possible carboligase enzyme.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0179","name":"ATP-grasp"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":475,"pathways":0,"proteins":475,"proteomes":251,"sets":1,"structural_models":{"alphafold":449},"structures":9,"taxa":521},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":49,"alignment:full":226},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"2r85","name":"Crystal structure of PurP from Pyrococcus furiosus complexed with AMP"}}}