{"metadata":{"accession":"PF06868","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009666","hierarchy":null,"name":{"name":"Protein of unknown function (DUF1257)","short":"DUF1257"},"description":[{"text":"<p>This family contains hypothetical proteins of unknown function that are approximately 120 residues long. Family members include eukaryotic and bacterial proteins. Members of this family are predicted to homodimerise by AlphaFold prediction.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":797,"pathways":0,"proteins":797,"proteomes":360,"sets":0,"structural_models":{"alphafold":467},"structures":0,"taxa":1030},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":50,"alignment:full":600},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}