{"metadata":{"accession":"PF06787","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009625","hierarchy":null,"name":{"name":"FeGP cofactor biosynthesis protein HcgF","short":"HcgF"},"description":[{"text":"<p>This archaeal family includes the iron guanylylpyridinol (FeGP) cofactor biosynthesis protein HcgF which catalyses the transesterification of AMP-GP to afford a Cys (HcgF)-S-GP thioester [[cite:PUB00098596]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00098596":{"PMID":25882909,"ISBN":null,"volume":"6","issue":null,"year":2015,"title":"Protein-pyridinol thioester precursor for biosynthesis of the organometallic acyl-iron ligand in [Fe]-hydrogenase cofactor.","URL":null,"raw_pages":"6895","medline_journal":"Nat Commun","ISO_journal":"Nat Commun","authors":["Fujishiro T","Kahnt J","Ermler U","Shima S."],"DOI_URL":null}},"set_info":{"accession":"CL0988","name":"HcgF"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":50,"pathways":0,"proteins":50,"proteomes":46,"sets":1,"structural_models":{"alphafold":46},"structures":3,"taxa":119},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":12,"alignment:full":22},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"3wva","name":"SeMet-labelled HcgF from Methanocaldococcus jannaschii"}}}