{"metadata":{"accession":"PF06760","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR010632","hierarchy":null,"name":{"name":"Protein of unknown function (DUF1221)","short":"DUF1221"},"description":[{"text":"<p>This is a family of plant proteins, most of which are hypothetical and of unknown function. All members contain the [pfam:PF00069] domain, suggesting that they may possess kinase activity.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":22,"interactions":0,"matches":972,"pathways":0,"proteins":961,"proteomes":344,"sets":0,"structural_models":{"alphafold":771},"structures":2,"taxa":928},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":17,"alignment:full":592},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}